Summary
Background
Contralateral Testis Hypertrophy (CTH) is a clinical marker that could be used to
guide the choice of the main surgical strategy. In patients with a Non-palpable Testis
(NPT), the degree of CTH as measured by testicular length or volume has been shown
to be able to predict whether the undescended testis will survive.
Objective
The purpose of this study was to establish the proper cut-off for identifying non-viable
testes based on the current literature.
Design
We systematically searched several medical databases as well as Google Scholar search
engines for references and citations. All the studies that reported CTH as a result
of NPT in prepubertal boys were included. Data from the included articles was gathered
by two independent reviewers. The checklist developed by the Joanna Briggs Institute
(JBI) was used to evaluate the methodological quality of the studies that were included.
Due to the incredibly high degree of heterogeneity among the studies, no meta-analysis
was done.
Results
The current systematic review included 17 studies that assessed the cut-off point
to detect non-viable testis. The size and length of the testes were taken into consideration
based on our findings. We found that different studies reported various ideal cut-off
values for predicting non-viable testes, which can be brought on by various measuring
techniques, evaluation ages, and patient groupings. The difference in testis volume
was greater than the difference in its length, which can be attributable to the fact
that some studies used an orchidometer to measure the testis's length directly or
indirectly.
Conclusion
According to the results of our study, it seems that defining a cut point for diagnosis
of CTH based on the size of the testis, cannot demonstrate the absence of a non-palpable
testis.
Keywords
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Article info
Publication history
Published online: March 13, 2023
Accepted:
March 8,
2023
Received in revised form:
November 21,
2022
Received:
August 28,
2022
Publication stage
In Press Journal Pre-ProofIdentification
Copyright
© 2023 Published by Elsevier Ltd on behalf of Journal of Pediatric Urology Company.