Summary
Introduction
Tissue glue has been examined extensively for its effectiveness in pediatrics, and
the findings are good. The purpose of this research was to examine the effectiveness
of tissue glue compared to absorbable sutures for wound approximation in pediatric
circumcision.
Methods
A systematic review and meta-analysis on children who had circumcision using tissue
glue and absorbable suture were done in line with the PRISMA criteria. RevMan 5.4
was used to perform the meta-analysis. The mean differences for continuous and dichotomous
data are determined using inverse variance, and the odds ratio is calculated using
the Mantel-Haenszel technique.
Results
The inclusion criteria were met by six trials containing a total of 817 patients.
According to the analysis, tissue glue significantly reduces the duration of the operation
(MD – 7.98; 95% CI -12.35, -3.62; p = 0.0003), pain severity (SMD -0.57; 95%CI -0.80,
-0.32; p < 0.00001) and the duration of pain (MD - 2.33; 95% CI -2.57, -2.08; p < 0.00001)
compared to absorbable suture. However, we found that there was no significant difference
in the incidence of postoperative bleeding, infection, dehiscence, or overall complication
when comparing tissue glue to traditional suture.
Conclusion
Our systematic review and meta-analysis using the most recent data suggest that tissue
glue usage might reduce the operation time, as well as the intensity and duration
of postoperative pain.
Keywords
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Article info
Publication history
Published online: March 22, 2022
Accepted:
March 10,
2022
Received in revised form:
March 8,
2022
Received:
December 11,
2021
Identification
Copyright
© 2022 Journal of Pediatric Urology Company. Published by Elsevier Ltd. All rights reserved.