Astaxanthin for testicular torsion

  • Consolato M. Sergi
    Correspondence
    Anatomic Pathology Division, Pediatric Pathologist, Children's Hospital of Eastern Ontario (CHEO), 401 Smyth Road Ottawa, ON K1H 8L1 Canada, Tel.: +613 737 7600; fax: +613 738 4837
    Affiliations
    Anatomic Pathology, Children’s Hospital of Eastern Ontario (CHEO), Canada
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Published:October 28, 2021DOI:https://doi.org/10.1016/j.jpurol.2021.10.019
      We read with interest the recent article of Dr. Baskovic on the use of astaxanthin for the ischemic process that occurs following the testicular torsion [
      • Bašković M.
      • Bojanac A.K.
      • Sinčić N.
      • Perić M.H.
      • Krsnik D.
      • Ježek D.
      The effect of astaxanthin on testicular torsion-detorsion injury in rats - detailed morphometric evaluation of histological sections.
      ]. Testicular viability in neonatal torsion is indeed generally poor. My experience at the Children's Hospital of Eastern Ontario (Ottawa, ON, Canada), and previously at the Stollery Children's Hospital (Edmonton, AB, Canada) mirrors the literature review. A survey of 18 case series with 284 patients found a salvage rate of less than 10% [
      • Nandi B.
      • Murphy F.L.
      Neonatal testicular torsion: a systematic literature review.
      ]. In addition, testicular torsion is associated often with hemorrhagic necrosis of the testis (Fig. 1). At the times of surgical exploration a contralateral orchiopexy has been suggested because the etiology for extravaginal torsion remains until now unclear.
      Fig. 1
      Fig. 1Hemorrhagic necrosis of the testis of a 9-years-old child following testicular torsion.
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