Abstract
Objective
The aim of this study was to measure the 24 h urinary calcium content in children
with monosymptomatic nocturnal enuresis (MNE) and compare with those in healthy children
to investigate whether there is any relation with enuresis and hypercalciuria.
Material and methods
This study included 120 children and adolescents with MNE aged between 7 and 14 years.
Eighty age- and sex-matched healthy children served as a control group. To determine
urinary calcium excretion, 24 h urine samples were collected. The children with enuresis
were divided into two sub-groups as hypercalciuric and normocalciuric groups according
to the amount of urinary calcium excretion.
Results
Hypercalciuria was found in 27 (23%) of the MNE patients compared with two (4%) of
continent children (p < 0.001). In addition, the mean 24 h urine calcium/body weight ratio was higher in
the enuresis group than in the control group, 2.94 ± 2.42 versus 1.59 ± 1.72, respectively
(p = 0.002). When the children with enuresis were divided into two groups as normokalsiuric
and hypercalciuric, the hypercalciuric children were younger and the majority of this
group were boys..
Conclusions
Our study showed that hypercalciuria is common in children with MNE, so we suggested
measuring urine calcium levels in NE patients. However, further studies are needed
to clarify the relationship between hypercalciuria and NE in larger series..
Keywords
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Article info
Publication history
Published online: June 04, 2014
Accepted:
April 14,
2014
Received:
October 24,
2013
Identification
Copyright
© 2014 Journal of Pediatric Urology Company. Published by Elsevier Inc. All rights reserved.
