Abstract
Objective
To evaluate the effectiveness of the first postnatal ultrasound (US) in predicting
the final postnatal diagnosis using a database of children followed prospectively
for antenatal hydronephrosis, and to compare these findings with a systematic review
of the literature.
Methods
The study involved 1441 children who had their radiological evaluation between 3 and
60 days of life, including an US, performed at our institution in 1998–2006. Univariate
and multivariate analyses were performed. A systematic review of articles on prenatal
hydronephrosis resulted in 31 studies with 2202 patients who met the inclusion criteria
for analysis.
Results
62.0% of renal units (RUs) had transient or non-obstructive hydronephrosis. Increasing
degree of hydronephrosis correlated with increased risk of urological pathologies
(from 29.6% RUs in the mild group to 96.3% RUs in the severe group). A systematic
review of the literature indicated very poor quality data, but the findings appeared
to be concordant with those from our patient population.
Conclusion
The findings from this study will help to quantify the incidence of postnatal pathology
based upon the first postnatal US parameters. This information is useful for counseling
and for determining which postnatal radiological tests will be necessary.
Keywords
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Article info
Publication history
Published online: October 18, 2010
Accepted:
September 7,
2010
Received:
July 24,
2010
Identification
Copyright
© 2010 Journal of Pediatric Urology Company. Published by Elsevier Inc. All rights reserved.