Journal of Pediatric Urology
Volume 7, Issue 4 , Pages 404-411 , August 2011

A biomechanical, histological and biochemical study in an experimental rabbit hypospadias repair model using scanning acoustic microscopy

  • Marianna Lalla

      Affiliations

    • Institute of Clinical Medicine, Aarhus University Hospital Skejby, Brendstrupgaardsvej 100, 8200 Aarhus N, Denmark
    • Department of Paediatric Urology, Afdeling K, Aarhus University Hospital Skejby, Brendstrupgaardsvej 100, 8200 Aarhus N, Denmark
    • Corresponding Author InformationCorresponding author. Department of Paediatric Urology, Afdeling K, Aarhus University Hospital Skejby, Brendstrupgaardsvej 100, 8200 Aarhus N, Denmark. Tel.: +45 8949 5926; fax: +45 8949 6006.
    • Present address: Great Ormond Street Hospital, Great Ormond Street, Urology Office, 7th floor Southward Building, London WC1N 3JH United Kingdom. Tel.: +44 0 2074059200x0203; fax: +44 0 2078138260.
    • ,
  • Carsten Riis

      Affiliations

    • Institute of Clinical Medicine, Aarhus University Hospital Skejby, Brendstrupgaardsvej 100, 8200 Aarhus N, Denmark
    • ,
  • Claus Schiøtt Jørgensen

      Affiliations

    • Institute of Clinical Medicine, Aarhus University Hospital Skejby, Brendstrupgaardsvej 100, 8200 Aarhus N, Denmark
    • ,
  • Carl Christian Danielsen

      Affiliations

    • Department of Connective Tissue Biology, Institute of Anatomy, University of Aarhus, building 1233, Wilhelm Meyers Allé 3, 8000 Aarhus C, Denmark
    • ,
  • Troels Munch Jørgensen

      Affiliations

    • Institute of Clinical Medicine, Aarhus University Hospital Skejby, Brendstrupgaardsvej 100, 8200 Aarhus N, Denmark
    • Department of Paediatric Urology, Afdeling K, Aarhus University Hospital Skejby, Brendstrupgaardsvej 100, 8200 Aarhus N, Denmark

Received 13 December 2009 ,Accepted 23 July 2010.

References 

  1. Lalla M, Danielsen CC, Austevoll H, Olsen LH, Jørgensen TM. Biomechanical and biochemical assessment of properties of the anterior urethra after hypospadias repair in a rabbit model. J Urol. 2007;177:2375–2380
  2. Sano H, Saijo Y, Kokubun S. Non-mineralized fibrocartilage shows the lowest elastic modulus in the rabbit supraspinatus tendon insertion: measurement with scanning acoustic microscopy. J Shoulder Elbow Surg. 2006;15:743–749
  3. Jensen AS, Baandrup U, Hasenkam JM, Kundu T, Jørgensen CS. Distribution of the microelastic properties within the human anterior mitral leaflet. Ultrasound Med Biol. 2006;32:1943–1948
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  7. Snodgrass W. Tubularized, incised plate urethroplasty for distal hypospadias. J Urol. 1994;151:464–465
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  9. Koff SA. Mobilization of the urethra in the surgical treatment of hypospadias. J Urol. 1981;125:394–397
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  11. Danielsen CC, Andreassen TT. Mechanical properties of rat tail tendon in relation to proximal-distal sampling position and age. J Biomech. 1988;21:207–212
  12. Gundersen HJ, Jensen EB. The efficiency of systematic sampling in stereology and its prediction. J Microsc. 1987;147:229–263
  13. Kundu T, Bereiter-Hahn J, Karl I. Cell property determination from the acoustic microscope generated voltage versus frequency curves. Biophys J. 2000;78:2270–2279
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  15. Genc A, Taneli C, Gunsar C, Turkdogan P, Yilmaz O, Arslan OA, et al. Histopathological evaluation of the urethra after the Snodgrass operation: an experimental study in rabbits. BJU Int. 2002;90:950–952
  16. Taneli F, Ulman C, Genc A, Yilmaz O, Taneli C. Biochemical analysis of urethral collagen content after tubularized incised plate urethroplasty: an experimental study in rabbits. Urol Res. 2004;32:219–222
  17. Horasanli K, Perk C, Yesildere T, Gumus E, Miroglu C. Healing of the urethral plate after deep incision: does catheterization change the course of this process?. Urol Int. 2007;78:249–253
  18. Baskin LS, Erol A, Li YW, Cunha GR. Anatomical studies of hypospadias. J Urol. 1998;160:1108–1115
  19. Erol A, Baskin LS, Li YW, Liu WH. Anatomical studies of the urethral plate: why preservation of the urethral plate is important in hypospadias repair. BJU Int. 2000;85:728–734

PII: S1477-5131(10)00404-3

doi: 10.1016/j.jpurol.2010.07.011

Journal of Pediatric Urology
Volume 7, Issue 4 , Pages 404-411 , August 2011

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