Journal of Pediatric Urology
Volume 1, Issue 1 , Pages 43-45, February 2005

Bladder necrosis presenting with hematuria in a patient with sickle-cell disease

  • N.S. Johal

      Affiliations

    • Department of Paediatric Urology, Institute of Urology, University College Hospital, London, UK
    • Corresponding Author InformationCorresponding author. Tel.: +44 79 70213970; fax: +44 14 88658358.
  • ,
  • D. Desai

      Affiliations

    • Department of Paediatric Urology, Institute of Urology, University College Hospital, London, UK
  • ,
  • A. Freeman

      Affiliations

    • Department of Pathology, University College Hospital, London, UK
  • ,
  • P.M. Cuckow

      Affiliations

    • Department of Paediatric Urology, Institute of Urology, University College Hospital, London, UK

Received 21 September 2004

Abstract 

We present an interesting case of bladder necrosis in an 11-year-old boy with sickle-cell disease. The patient initially presented with sudden onset of abdominal pain and went on to have gross hematuria with clots and severe dysuria. Cysto-urethroscopy revealed global hemorrhagic cystitis and a suprapubic catheter was inserted percutaneously during cystoscopy. The symptoms spontaneously resolved over several weeks and the child voids normally at last follow-up. Multiple bladder biopsies were taken and all were completely necrotic.

Keywords: Bladder necrosis, Hematuria, Sickle-cell disease, Genitourinary system

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PII: S1477-5131(04)00004-X

doi:10.1016/j.jpurol.2004.11.002

Journal of Pediatric Urology
Volume 1, Issue 1 , Pages 43-45, February 2005